Minimally invasive single-cell injection using a nanopipette
Adopted glass pipette (nanopipette) with tip size of under 100 nanometers for minimally invasive injection.
Automatic Cell Detection and Penetration
The ion current measurement detects the nanopipette tip as it approaches a cell’s surface. Automatic depth penetration can be controlled at a speed which minimizes damage to the cell.
Injection using electrochemical phenomena
Utilizes electrochemical phenomena in the tip of the nanopipette to inject target substances into the selected cell.
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Minimally Invasive Intracellular Nano-Injector
This system component automates the penetration and injection of single cells using a nanopipette. It‘s low invasiveness enables manipulation of live single cells. The system integrates with multiple manufacturers’ inverted microscopes.
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Subcellular Sampling System SS2000
The SS2000 is a system that automatically samples specific regions of cells or whole cells at the single-cell level while imaging cells in culture with a confocal microscope. Because cells in culture do not need to be detached, positional and morphological information is maintained.
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YOKOGAWA will contribute to technology evolution particularly in measurement and analytical tools to help build a world where researchers will increasingly focus on insightful interpretation of data, and advancing Life Science to benefit humanity.
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